Research Spotlight

So much of science and medicine comes down to taking pictures. Biology, especially, has long been considered an observational enterprise.

The most lethal part of cancer is that it spreads.

Stopping the spread of cancer, known as metastasis, would be a leap forward in treatment. However, first, we must better understand why and how metastasis happens.

Cancer is not just one disease. Were it, we could imagine a single cure. Instead, we find that cancer is a mix of clinically separable diseases.

Mitochondria are the powerhouses of the cell. These organelles support cellular functions through ATP production and have been implicated in diseases ranging from cancer to Parkinson’s. Additionally, their function extends beyond energy.

Image of neuron.
Consider brains and computers. How are they similar? Both can perform complex, rational tasks. Both take inputs and make decisions. More generally, both occupy physical space, although computers increasingly less so. As part of their physical nature, both can be subdivided into parts, the organization and connectivity of which creates their function.

Tauopathies are a spectrum of neurodegenerative diseases defined by their cellular pathology. Their name refers to the protein tau which aggregates pathologically in clumps known as fibrils.

In 2015, evolution is considered an older discovery, and perhaps seems dusty to a generation piqued by CRISPR gene editing, pluripotent stem cells, and the still opaque mysteries of the microbiome.
Reviews of journal articles covering topics of Cancer Biology, Biochemistry & Cancer Biology, Infectious Disease, and Immunology.
Reviews of journal articles covering topics of Physiology, Developmental & Evolutionary Biology, Immunology, and Microbiology.
Reviews of journal articles covering topics of Structural Biology, Genetics & Autoimmunity, Cancer Biology, and Neuroscience.