Science

This past weekend I sliced my finger while attempting to slice a carrot. The Wusthof cut through the nail on my left pinkie, aggravating a piece of flesh that, until that point, had successfully avoided combat.

Reproducibility in biological research — or more specifically the lack of it — is an ongoing issue.

Cancer begins from a single mutation in a single cell. By the time it is a full-blown tumor, it carries hundreds of genetic and molecular alterations that allow it to grow uncontrollably outside the constraints of normal biology.

As you read these words, hold out your hand. Notice the space between your fingers, the fragments of MacBook you can see through these windows. Think about how these digits formed, precisely arrayed and extended.

Today, HIV infection is no longer a death sentence for those with access to anti-retrovirals. These drugs suppress replication of the virus and keep viral levels low in patients. However, as HIV patients on anti-retrovirals age, they show higher rates of age-related diseases, such as cancer and cardiovascular diseases. Understanding HIV pathogenesis is the focus of the laboratory of Warner C. Greene MD PhD, HIV expert and Director of the Gladstone Institute of Virology and Immunology.
Although it can be cooked in a separate pot, stuffing is traditionally cooked right inside the turkey, absorbing the bird’s flavorful juices and coming out moister than its stovetop counterpart.

So much of science and medicine comes down to taking pictures. Biology, especially, has long been considered an observational enterprise.

The most lethal part of cancer is that it spreads.

Stopping the spread of cancer, known as metastasis, would be a leap forward in treatment. However, first, we must better understand why and how metastasis happens.

Meat

Red wine. Coffee. Dark chocolate. Epidemiologists, doctors, and nutrition scientists are constantly analyzing the good and bad consequences of different food and beverage components of our diets and reporting correlative data.

Cancer is not just one disease. Were it, we could imagine a single cure. Instead, we find that cancer is a mix of clinically separable diseases.